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Explore 193 profitable Franchise Opportunities in Mid South. Whether you are looking for established franchises, e-commerce stores, or retail opportunities, we connect you with the perfect venture. Find your ideal investment today, leverage proven systems, and take the next step toward successful entrepreneurship across Mid South.
Own a tech-enabled, 24/7 indoor sports facility with RunRec, combining staffless operations, recurring memberships and multiple revenue streams across basketball, volleyball, pickleball and badminton. More details »
Average SDE: $832,294/year (3-Year Average) Established, multi-unit non-surgical medical practice generating an average of $3.5M+ in annual revenue and $832K+ in EBITDA over the last three years... More details »
Skip the years it takes to build a fencing business from zero and take over 4 active territories already operating across North Texas. This Top Rail Fence franchise resale covers residential... More details »
Own a fast-growing indoor play franchise combining entertainment, learning, and family experiences through immersive construction-themed play and multiple revenue streams. More details »
This is a great opportunity to purchase a top rated B2B signs and graphics franchise brand that has a long history of producing fantastic results. The business is located in Dallas in a prime... More details »
Well-established, profitable staffing and recruiting agency in Tupelo, MS. This is an excellent opportunity for a new owner to take over an established agency and take results to the next level. Full... More details »
Own a cutting-edge Body Sculpting studio with a lean team, high-ticket services, and done-for-you marketing—ideal for executive or semi-absentee owners looking to scale in the U.S. beauty sector. More details »
Reduced Asking Price! Established staffing and recruiting agency in Rolla, MO. This is an excellent opportunity for a new owner to take over an established agency and build on a nice client base to... More details »
Motivated Seller is ready to retire! This established B2B signs and large format printing franchise represents a compelling acquisition opportunity in the southwest area of the greater Houston metro... More details »
Own a luxury media franchise, sell premium ad space in a world-renowned magazine, benefit from zero production overhead, global prestige, local appeal, and high profit margins More details »
Take advantage of a rare opportunity to step into ownership with Amazing Lash Studio, one of the most recognized and in-demand brands in the beauty industry. Rather than starting from scratch, you’ll... More details »
Take over 3 built-out Barry Bagels stores already open and running, without spending the year and roughly $1M it took to build them from scratch. This is a hub-and-spoke Barry Bagels operation in... More details »
Own a high-profit, work-from-home business in a recession-resistant industry with minimal competition, unlimited earning potential, complete business setup, and ongoing expert support. More details »
Available opportunity to acquire a portfolio of three established UPS Stores located in a fast growing region of the Alabama. This multi-unit group benefits from strong brand recognition, diversified... More details »
Average SDE: $567,000/year (3-Year Average) Established non-surgical medical practice generating an average of $2.3M+ in annual revenue and $567K+ in SDE over the last three years. Unlike many... More details »
Hydrodog franchising gives you a mobile grooming model built for growth. Low overhead, high demand, and smart support that shows up when you need it. More details »
Buying this established massage franchise means you’re stepping into a business with a loyal customer base, trained staff, and steady membership revenue from day one. It’s a turnkey opportunity with... More details »
We are delighted to present the rare opportunity to own one or two Fuzzy's Taco Shops – well known for a colorful and uplifting, fun atmosphere. All orders are made from scratch, giving the customer... More details »
A modern, tech-forward roofing franchise with low overhead, strong ROI potential, and a simple, transparent model that makes ownership accessible and profitable. More details »
Asking Price: ~$1,400,000 (Total Package) Location: Houston, TX. Health And Wellness / Medical Spa Franchise Owner Involvement: Passive — No daily management required. Rare opportunity to acquire a... More details »
Asking Price: ~$1,400,000 (Total Package) Location: Nashville, TN. Health & Wellness / Medical Spa Franchise Owner Involvement: Passive — No daily management required. Rare opportunity to acquire a... More details »
Join Smoky Grass Station, a trusted hemp extract and smoke shop brand with proven success, full training, marketing support, and growth opportunities in a thriving industry. More details »
Asking Price: ~$1,400,000 (Total Package) Location: Dallas-Fort Worth, TX. Health & Wellness / Medical Spa Franchise Owner Involvement: Passive — No daily management required. Rare opportunity to... More details »
This established staffing and workforce solutions business is generating approximately $290,503 in annual gross commission revenue (Office gross revenue much more) and $94,954 in Seller's... More details »
Own a fast-casual superfood cafe with strong demand for healthy, allergy-friendly meals. Vitality Bowls delivers premium bowls, smoothies, and community impact with strong franchisor support. More details »
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